melissa officinalis como alternativa terapêutica no tratamento da ansiedade e do estresse: uma revisão de literatura

Abstract

This study addresses the use of Melissa officinalis as a therapeutic alternative for the treatment of anxiety and stress through a bibliographic review of its phytochemical, pharmacological, and therapeutic aspects. The research is based on the increasing occurrence of anxiety and stress disorders in modern society and the growing search for natural treatments with fewer side effects. This is an integrative review conducted across the PubMed, SciELO, ScienceDirect, and Portal CAPES databases, encompassing publications released between 2015 and 2026, aiming to identify the main chemical compounds present in the plant, its anxiolytic and relaxing properties, and possible toxicity levels. The results indicate that Melissa officinalis contains bioactive compounds such as flavonoids, phenolic acids, and essential oils that act on the central nervous system, contributing to the reduction of symptoms associated with stress and anxiety. The study also highlights the importance of the safe use of herbal medicines according to recommendations from regulatory institutions. Therefore, the research organizes scientific and traditional information about the plant, encouraging future experimental studies and expanding discussions on the use of natural products in health care.