Análise do perfil químico e biológico do extrato etanólico das folhas da espécie Kalanchoe daigremontiana

Abstract

Over the centuries, ancient civilizations used plants as an important therapeutic resource in curing various diseases. These medicinal properties attributed to plant species are derived from secondary metabolites. Among the countless plant species, we can mention the Kalanchoe daigremontiana popularly known as aranto or mother of-thousands, the cultivation of this species is due to its great ornamental and medicinal value in curing diseases such as sore throats and in the treatment of other inflammations. In this context, the present work aims to investigate the chemical profile, content of total phenolic compounds and toxicity of the ethanolic extract from the leaves of kalanchoe daigremontiana. In carrying out this research, an ethanolic extract from the leaves of the Kalanchoe daigremontiana species was prepared, yielding a yield of 10.38%, which was subsequently subjected to qualitative phytochemical tests which allowed the presence of phenolic compounds and free steroids to be identified, Then, total phenols were quantified using the Folin-Ciocalteu method with a gallic acid calibration curve, which presented results of 575.5 mg, corroborating the qualitative analysis of the extract. The toxicity test showed 3.33% mortality of Artemia salina naupiles at concentrations of 1000 ppm, being considered non-toxic in this test. Therefore, new research must be carried out with this extract in order to characterize the antioxidant activity in vivo, as well as other activities and characterization of chemical structures.