Avaliação do potencial citotóxico em infusões de folhas de morus nigra utilizadas para fins terapêuticos

Abstract

The use of medicinal plants for the treatment of various diseases is a common practice in many cultures around the world. However, indiscriminate use can lead to adverse effects, such as cytotoxicity. In this context, the present study aims to evaluate the cytotoxic potential of mulberry leaf tea at different concentrations, using the Allium cepa test system. To evaluate the cytotoxic potential of mulberry leaf tea, the methodology employed in the articles by DA SILVA et al. (2010) and ARRAES et al. (2012) was followed. Five assays were performed with four replicates each, with one control group. The bulbs were rooted in distilled water, and after 5 days, the roots were cut to have the same length. The other bulbs were divided into 4 groups and placed in contact with infusions prepared with different concentrations of mulberry leaves. The contact between the roots and the teas lasted for 11 days, and root growth was evaluated compared to the control group. The results indicated that the control group had the greatest root development, while the groups that were exposed to the tea showed a significant reduction in growth. The group that was exposed to the highest concentration of tea showed the greatest reduction in root growth and also had larvae in some of the bulbs. The informational brochure was created to raise awareness among the population about the dangers of using teas prepared with high concentrations. The brochure was disseminated through Instagram, on the @BIOTECPI_FLORA profile - Biodiversity and Biotechnology Research Group of Centro-Norte Piauiense.