Síntese e caracterização de um compósito formado por quitosana e extrato de (cinnamomum zeylanicum) com potencial aplicação na regeneração tecidual

Abstract

Chitosan is a polymer produced by the deacetylation of chitin and has been investigated for several applications as a biomaterial due to its characteristics, such as biocompatibility and non-toxicity, as well as antimicrobial and curative actions, and these functions can be potentiated with the incorporation of others, and with other agents they have shown the intended results for the purpose of defining the association by means of chitosan composites formers. The objective of this study was the development and protection of chitosan-based membranes (MQ) and chitosan composites associated with the attached aqueous extract of Cinnamomum for biological/pharmacological applications as an aid in the tissue characterization process. Absorption capacity and mass loss assays were carried out in distilled water and artificial saliva, X-ray Fluorescence (FRX), Differential Scanning Calorimetry (DSC), Thermogravimetry (TG), wettability, toxicity, biocompatibility assessment through body fluid (SBF), pH and electrical conductivity. The water absorption tests can be considered as a relevant absorption capacity since it can bring a membrane of high stability for example polymeric biomaterials as the reduction of the structural studies of the polymer can be considered as a reduction of the structurally polymeric studies as the reduction of the Structural studies of the polymer can be considered as a reduction of structurally polymeric studies that can be considered as a reduction of structural studies of the polymer. The degradation assays in the membranes show a better stability in the membranes when associated with the extract, the degradation assays in the membranes indicate a lower degradability in the membranes associated with the extractor, reinforcing the thermogravimetric results The in vitro assays through the analysis of pH, conductivity and biocompatibility in SBF, pointed out the new composite with potential for application in health, as an implantable device for tissue health.