Preparo e caracterização de membranas de quitosana incorporadas com pó rico em carbonato de cálcio extraído das casca de ovo de galinha caipira (gallus gallus domesticus)

Abstract

The amount of materials developed for application in living models has become increasingly larger and in this respect those related to short-term bone regeneration, among them bioceramics such as calcium carbonate and biopolymers such as chitosan, are highlights. Chitosan is a biopolymer that has established active principles such as: biocompatibility (low toxicity), biodegradability, healing effect, blood cholesterol level control, antimicrobial, coagulant, analgesic, treatment of osteoarthritis among others, and the use of calcium carbonate Is advantageous because it is a biocompatible material and has a suitable rate of biodegradation. Chitosan is already used in the production of polymeric membranes applications in dressings for tissue regeneration mainly epithelial. In this work the preparation and characterization of chitosan membranes incorporated with calcium carbonate-rich powder obtained from hen's egg shell (Gallus gallus domesticus) was carried out to propose a new biomaterial. Membranes were prepared with different concentrations of 1% and 1.5% chitosan, with mass dispersions of 1%, 5% and 10% of powder. The results of infrared, SEM, XRD and FRX presented data showing the incorporation of the calcium carbonate rich powder to the polymer matrix in the different concentrations evaluated (1% and 1,5%). The micrographs of the membranes showed particles of the calcium carbonate rich powder in different forms, and the diffractograms showed a favored calcite phase verified through the visualization of an intense peak characteristic for this phase. Based on FRX results, it was evaluated that hen egg hulls can be classified as an acceptable and sustainable source to obtain calcium carbonate, since they presented a high calcium content 98, 755%, thus contributing as a new Proposed to be used in the preparation of new biomaterials mainly those related to the regeneration of bone tissue. The membranes presented a hydrophilic profile.